Potential Consequences of Long Term Amphetamine Use
Psychological shifts such as hyperfocus on tasks, irritability when interrupted, or sudden bouts of anxiety—especially as the drug wears off—are also telling. Chronic users may develop a “crash” phase marked by extreme fatigue, depression, or emotional numbness between doses. High doses of amphetamines can produce psychotic behavior indistinguishable from schizophrenia in asymptomatic schizophrenics and in some healthy human subjects 190, 191. The Diagnostic and Statistical Manual of Mental Disorders, Fourth https://jobs.mobilecooks.com/how-to-get-rid-of-the-spins-when-drunk-stop/ Edition (DSM-IV) recognizes diagnoses of amphetamine-induced psychotic disorder with delusions and amphetamine-induced psychotic disorder with hallucinations. In one study of healthy volunteers, repeated administration of 5−10 mg of oral dextroamphetamine produced paranoid delusions in all subjects at cumulative dosages between 55 and 75 mg 192. The current illicit amphetamine epidemic is increasing the incidence of this problem.
Why is this medication prescribed?
In 1991, the United States Federal Education Department began classifying ADHD as an educational disability in terms of the Individuals with Disabilities Education Act. This act mandates a comprehensive behavioral, educational and medical evaluation of children suspected of having an educational disability. A physician visit is not required, but the school district is obligated to provide any diagnostic services that are needed at no cost to parents 12. Over the next 2 years, ADHD diagnoses tripled, from one to three million.
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Store it at room temperature and away from light, excess heat and moisture (not in the bathroom). Tell your doctor if you or anyone in your family drinks or has ever drunk large amounts of alcohol, uses or has ever used street drugs, or has overused prescription medications. Your doctor may want to run a few tests to see if you have conditions that might not mix well with ADHD drugs. For instance, they can check to see if you have high blood pressure, an irregular heartbeat, or other kinds of heart disease. They might crush the pills and snort them to get high, which can lead to a dangerous overdose.
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It is important to understand the physical and psychological impact that this drug can have on individuals. Additionally, the allure of Adderall as a cognitive enhancer has contributed to its misuse. Many individuals, especially students and young adults, have turned to Adderall to enhance their cognitive performance. The drug is reputed for its ability to boost concentration, energy levels, and alertness, making it an appealing choice for those seeking an academic or professional edge.
- Over time, the chemical imbalances brought on by long term amphetamine use start to interfere with the brain’s cognitive-based centers, most especially the brain’s reward system.
- Therefore, it’s essential to be aware of the potential risks before taking this type of drug.
- Involving family and friends during counseling can help support you and keep you from going back to using (relapsing).
- The FDA suggests people with a history of those problems stay away from it.
By raising awareness, providing support, and promoting responsible medication use, we can work towards creating a safer and healthier environment for all. The competitive nature of higher education, combined with the desire to achieve academic success, has created an environment where students are willing to go to extreme lengths to gain an advantage. The misuse of Adderall has Amphetamine Addiction become a common practice among students who believe it will help them stay focused and study for extended periods without fatigue. It is important to note that Adderall should only be used under the supervision and guidance of a healthcare professional. The dosage and duration of use are determined based on the individual’s specific needs and response to the medication.
In the 1990s, longer acting forms of amphetamine were developed using capsules of mixed d- and l- salts in both immediate release pellets and enteric-coated, delayed-release beads. The different salts and beads are metabolized at different rates, resulting in a less dramatic onset and termination of therapeutic action. Amphetamine is most often administered twice daily in immediate-release formulations (Dexedrine, DextroStat, or Adderall IR tablets), or once a day in sustained-release formulations (Dexedrine or Adderal XR capsules, Vyvanse tablets). The therapeutic effects begin within 45−60 min after ingestion of an immediate-release tablet, with peak effect in 2 to 3 hours, and a total duration of 4−6 h.
- Adderall is a combination of amphetamine and dextroamphetamine that stimulates the central nervous system by increasing dopamine and norepinephrine levels in the brain.
- The chronic effects of amphetamine include a condition called rhabdomyolysis which results from an overactive metabolism in the muscles and leads to kidney failure.
- Detailed discussion of these epidemics goes beyond the scope of this review, but they continue to be a substantial international public health problem, as detailed in a recent supplement of the journal “Addiction” 76.
- Studies estimate that up to 30% of college students in the U.S. have used stimulants like Adderall without a prescription, often during exam periods or while juggling multiple deadlines.
In 1991, there were still fewer than 500,000 annual prescriptions written for amphetamine in the US. Over the ensuing decade and a half, however, the alcohol rehab amount of amphetamine produced and the number of prescriptions written in the United States increased dramatically. Overcoming an amphetamine addiction can be difficult due to the severe withdrawal symptoms that users experience when they try to quit.
Risk Factors Of Prescription Amphetamine Abuse
Long-term amphetamine abuse can lead to severe consequences on physical and mental health. Prolonged use may result in cardiovascular damage, including heart disease, heart rhythm abnormalities, and high blood pressure. Increased HIV and hepatitis B and C transmission are possible related consequences of increased methamphetamine abuse, not only in individuals who inject the drug but also in non-injecting methamphetamine abusers.

They can also tell you which side effects need immediate care and which can wait for an appointment. Amphetamines (pronounced “am-FET-uh-meens”) make your body release extra dopamine and norepinephrine. The more of them you have circulating in your body, the more active the affected systems are. Amphetamines also make these neurotransmitters stick around in your body longer. Join 40,000+ People Who Receive Our Newsletter Get valuable resources on addiction, recovery, wellness, and our treatments delivered directly to your inbox. Much like a physical dependency, a person’s life circumstances will only worsen with continued drug use.
- Amphetamine addiction is a serious issue that affects individuals worldwide.
- For non-prescription products, read the label or package ingredients carefully.
- Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
- But your healthcare provider is there to guide you and make sure these drugs are safe and effective.

Though it’s statistically rare for an Adderall user to develop psychosis, one study found it to occur in one in every 660 patients. The reason Adderall is effective is that it increases dopamine, the brain’s “feel good” hormone, which can improve your mood and focus. The problem is that frequent changes in dopamine levels can also trigger mental health impairments like depression and anxiety. Additionally, Adderall can cause insomnia, which may exacerbate any existing mental health problems. Statistics curated by the National Institute on Drug Abuse show that about 2 in 3 teens and young adults who abuse prescription stimulants obtain the drug from non-prescription sources. Further, a 2018 study found that 11% of college students said they used Adderall without a prescription.
